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Uncovering the mechanisms of diosmin in treating obesity-related kidney injury based on network pharmacology, molecular docking, and in vitro validation

2024-07-29

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Obesity increases the risk of kidney injury, involving various pathological events such as inflammation, insulin resistance, lipid metabolism disorders, and hemodynamic changes, making it a significant risk factor for the development and progression of chronic kidney disease. Diosmin, a natural flavonoid glycoside, exhibits anti-inflammatory, antioxidant, anti-l...

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Literature Corpus work
3a1247dc-ed85-539c-b828-7b23f211e558
DOI
10.21203/rs.3.rs-4675276/v1
Open publication

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Uncovering the mechanisms of diosmin in treating obesity-related kidney injury based on network pharmacology, molecular docking, and in vitro validationDOI 10.21203/rs.3.rs-4675276/v1
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