Article

Molecular Landscape of Modality-Specific Exercise Adaptation in Human Skeletal Muscle through Large-Scale Multi-OMICs Integration

2024-07-15

Abstract excerpt

<h4>Summary</h4> We conducted a large-scale, statistically powered, meta-analysis of exercise adaptations in human skeletal muscles, integrating epigenetic, transcriptomic, transcription factors, and proteomic data across 12 independent cohorts comprising over 1000 participants and 2340 human muscle samples. Our study identified distinctive signatures associated with maximal oxygen consumption (VO 2max ), and id...

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Literature Corpus work: 064e95c5-8979-5710-b146-4003a23baa54
DOI: 10.1101/2024.07.14.603458

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