Article

Etifoxine inhibits NLRP3 inflammasome activity in human and murine myeloid cells

2023-09-21

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Multiple sclerosis (MS) is a chronic neuroinflammatory disease that is characterized by immune-mediated demyelination within the central nervous system. NLRP3 inflammasome activation has been previously reported as a possible pathophysiological contributor to microglial activation and oligodendroglial loss in MS, particularly in progressive forms of the disease. <h4>Methods<...

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Literature Corpus work: dca55d28-a9a0-5b42-8f34-644238291046
DOI: 10.1101/2023.09.19.558428

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