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Multi-Omics-Based Sex Stratification Identifies Distinct High-Risk Phenotypes in HFpEF

2026-07-13

Abstract excerpt

<h4>Background</h4> Heart failure with preserved ejection fraction (HFpEF) accounts for more than half of heart failure cases and is characterized by substantial clinical and biological heterogeneity. Sex differences are central to HFpEF pathophysiology, yet current phenotyping approaches often aggregate women and men, potentially obscuring distinct molecular mechanisms of disease progression. Molecularly resolve...

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Literature Corpus work
dc80b2e2-7d4d-5f99-8f4a-32ce26490041
DOI
10.64898/2026.07.09.26357645
Open publication

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