Article

Multicenter HFpEF study identifies sex disparity linked with two discrete cardiac proteomic signatures

2025-12-20

Abstract excerpt

Heart failure with preserved ejection fraction (HFpEF) is epidemic, with an incidence exceeding that of heart failure with reduced ejection fraction (HFrEF). Sex differences in HFpEF phenotype have been observed, particularly linked to aging and metabolic comorbidities in women. Here, we report a multi-centre proteomic analysis of HFpEF and HFrEF cardiac samples. Using tissues and clinical data derived from multip...

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Literature Corpus work: 6a26397c-b6d1-5496-8259-28c336d0f43b
DOI: 10.64898/2025.12.18.695212

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