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Article

Systemic Biomarkers and Unique Pathways in Different Phenotypes of Heart Failure with Preserved Ejection Fraction.

Biomolecules - 4 Oct 2022

Chen Hao, Tesic Milorad, Nikolic Valentina N, Pavlovic Milan, Vucic Rada M, Spasic Ana, Jovanovic Hristina, Jovanovic Ivana, Town Stephanie E L, Padula Matthew P, McClements Lana

Abstract excerpt

Heart failure with preserved ejection fraction (HFpEF) accounts for around 50% of all heart failure cases. It is a heterogeneous condition with poorly understood pathogenesis. Here, we aimed to identify unique pathogenic mechanisms in acute and chronic HFpEF and hypertrophic cardiomyopathy (HCM). We performed unbiased, comprehensive proteomic analyses of plasma samples from gender- and BMI-matched patients with...

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Identifiers

PMID: 36291628
DOI: 10.3390/biom12101419
PMCID: PMC9599828

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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