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Fecal HBA mRNA as an Alternative to the Protein-based FIT Assay for Colorectal Cancer Screening: A Computational and Clinical Validation Study

2025-09-16

Abstract excerpt

<title>Abstract</title> <p>Background: Current US FDA cleared stool based colorectal cancer (CRC) molecular screening tests include fecal immunochemical tests (FIT) for occult blood detection, but integration with nucleic acid-based biomarkers requires separate workflows, increasing complexity and cost. Objective To evaluate fecal hemoglobin alpha (HBA) mRNA as an RNA workflow compatible alternative to FIT, enabl...

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Literature Corpus work
dc74355c-9dc2-5e7f-b940-2388f1909d1f
DOI
10.21203/rs.3.rs-7604040/v1
Open publication

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Fecal HBA mRNA as an Alternative to the Protein-based FIT Assay for Colorectal Cancer Screening: A Computational and Clinical Validation StudyDOI 10.21203/rs.3.rs-7604040/v1
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