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Bioinformatic Screen with Clinical Validation for the Identification of Novel Stool Based mRNA Biomarkers for the Detection of Colorectal Lesions Including Advanced Precancerous Lesions

2025-07-18

Abstract excerpt

Messenger RNA (mRNA) stool based biomarkers represent a promising approach for the diagnosis of colorectal cancer (CRC) and advanced precancerous lesions (AA). But it is unclear which mRNA biomarkers have the most clinical utility. This study aims to partially fill this gap by performing an analysis which first ranks genes based on their expression profile in RNA-seq tissue datasets. The diagnostic performance of...

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Literature Corpus work
2aa9369a-8993-5fb3-bce0-2e77e6f5e59b
DOI
10.1101/2025.07.16.25331674
Open publication

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Bioinformatic Screen with Clinical Validation for the Identification of Novel Stool Based mRNA Biomarkers for the Detection of Colorectal Lesions Including Advanced Precancerous LesionsDOI 10.1101/2025.07.16.25331674
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