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Article

Multitarget stool DNA testing for colorectal-cancer screening.

The New England journal of medicine - 3 Apr 2014

Imperiale Thomas F, Ransohoff David F, Itzkowitz Steven H, Levin Theodore R, Lavin Philip, Lidgard Graham P, Ahlquist David A, Berger Barry M

Abstract excerpt

BACKGROUND: An accurate, noninvasive test could improve the effectiveness of colorectal-cancer screening. METHODS: We compared a noninvasive, multitarget stool DNA test with a fecal immunochemical test (FIT) in persons at average risk for colorectal cancer. The DNA test includes quantitative molecular assays for KRAS mutations, aberrant NDRG4 and BMP3 methylation, and β-actin, plus a hemoglobin immunoassay....

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Source

Identifiers

PMID: 24645800
DOI: 10.1056/NEJMoa1311194

Genes

BMP3
KRAS
NDRG4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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