Article

Genes Encoding Xenobiotic Detoxification Proteins evolve by gene death, duplication and positive selection

2025-06-01

Abstract excerpt

<h4>ABSTRACT</h4> There was a huge variability in the pharmacokinetics of drugs between species, which means in the way it will be transformed, degraded and eliminated, as well as the variation in drug absorption, plasma concentration over time, half-life, bioavailability, volume of distribution, metabolism rate, and routes of excretion. To understand the reasons of such a variability between species, we have stu...

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Literature Corpus work: dc6b3ee0-b65c-5711-816d-0e5b256cdd25
DOI: 10.1101/2025.05.31.657154

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