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Article

Evolution of ABC transporters by gene duplication and their role in human disease

2 Jan 2011

Abstract excerpt

The ATP-binding cassette (ABC) transporter genes represent the largest family of transporters and these genes are abundant in the genome of all vertebrates. Through analysis of the genome sequence databases we have characterized the full complement of ABC genes from several mammals and other vertebrates. Multiple gene duplication and deletion events were identified in ABC genes in different lineages indicating...

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PMID: 21194360
DOI: 10.1515/bc.2011.006

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