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Identification of Hub Genes Involved in Early-onset Schizophrenia: From Genetic Susceptibility to Predicted Regulated Gene Expression

2025-01-20

Abstract excerpt

<title>Abstract</title> <p>BACKGROUND Despite a high heritability of schizophrenia (SZ), only limited variance was attributed to gene loci or the polygenic risk score in genome-wide association studies (GWAS). Early-onset SZ, a more homogeneous SZ subtype, may aid in bridging the genotype-phenotype gap and the identification of its hub genes is critical for early intervention in clinical practice. We aimed to ex...

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Literature Corpus work: dc4dd2e3-0c9a-5341-8977-7da596c46ac1
DOI: 10.21203/rs.3.rs-5833160/v1

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