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Article

Identification of microRNAs in skeletal muscle associated with lung cancer cachexia

11 Dec 2019

Abstract excerpt

BACKGROUND: Cachexia, highly prevalent in patients with non-small cell lung cancer (NSCLC), impairs quality of life and is associated with reduced tolerance and responsiveness to cancer therapy and decreased survival. MicroRNAs (miRNAs) are small non-coding RNAs that play a central role in post-transcriptional gene regulation. Changes in intramuscular levels of miRNAs have been implicated in muscle wasting...

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PMID: 31828982
DOI: 10.1002/jcsm.12512

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