Article

Diet-induced hyperplastic expansion in subcutaneous adipose tissue and protection against adipose progenitor exhaustion in female mice are lost with ovariectomy

2024-09-06

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> The protection of females against cardiometabolic disease is in part attributable to a tendency for fat accumulation in subcutaneous depots, which promote lipid homeostasis by serving as a metabolic sink. At menopause this protection is lost, and body fat distribution resembles the male-like pattern of visceral adiposity. Adipose progenitor cells (APCs) can be recruited to s...

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Literature Corpus work: db7bce3d-2491-561f-9dad-ca0398c26aa2
DOI: 10.1101/2024.09.05.611480

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