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Article

Transcriptomic profiling reveals sex-specific molecular signatures of adipose endothelial cells under obesogenic conditions

16 Dec 2022

Abstract excerpt

Female mice display greater adipose angiogenesis and maintain healthier adipose tissue than do males upon high-fat diet feeding. Through transcriptome analysis of endothelial cells (EC) from the white adipose tissue of male and female mice high-fat-fed for 7 weeks, we found that adipose EC exhibited pronouncedly sex-distinct transcriptomes. Genes upregulated in female adipose EC were associated with...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 36624843
DOI: 10.1016/j.isci.2022.105811

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