Article

Comprehensive Analysis of LIN28A in Chinese Patients with Early Onset Parkinson’s Disease

2021-03-22

Abstract excerpt

<title>Abstract</title> <p>A loss-of-function variant in Lin-28 Homolog A gene (<italic>LIN28A</italic> p.R192G, rs558060339) has been identified in two East Asian ancestry patients with early-onset PD (EOPD). Functional studies revealed that such variant could lead to developmental defects and PD-related phenotype, and the phenotypes could be rescued after correction of the variant. The aim of the study was to s...

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Literature Corpus work: db71350a-97bb-5963-afbe-77fcb37b5926
DOI: 10.21203/rs.3.rs-326030/v1

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