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Whole-exome sequencing in early-onset Parkinson's disease among ethnic Chinese.

Neurobiology of aging - 1 Jun 2020

Li Nannan, Wang Ling, Zhang Jinhong, Tan Eng-King, Li Junying, Peng Jiaxin, Duan Liren, Chen Chaolan, Zhou Dong, He Li, Peng Rong

Abstract excerpt

Although early-onset Parkinson's disease (EOPD) has a more penetrant genetic etiology, the genetic architecture of EOPD remains unclear. The objectives of this study were to assess the genetic and clinical features of EOPD among ethnic Chinese from mainland China. Using whole-exome sequencing, we performed genetic analyses of 240 participants including 193 with sporadic and 47 with familial EOPD (age of onset...

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PMID: 32171587
DOI: 10.1016/j.neurobiolaging.2019.12.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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