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Article

Stereoelectronic Effects Impact Glycan Recognition

2020-01-09

Abstract excerpt

Recognition of distinct glycans is central to biology, and lectins mediate this function. Lectin glycan preferences are usually centered on specific monosaccharides. In contrast, human intelectin-1 (hItln-1, also known as Omentin-1) is a soluble lectin that binds a range of microbial sugars, including β-Dgalactofuranose (β-Galf), D-glycerol 1-phosphate, D-glycero-D-talo-oct-2-ulosonic acid (KO), and 3- deoxy-D-man...

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Literature Corpus work
db69d79a-5811-5395-abc8-20f1813c43e3
DOI
10.26434/chemrxiv.11541927.v1
Open publication

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Stereoelectronic Effects Impact Glycan RecognitionDOI 10.26434/chemrxiv.11541927.v1
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