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A Boltzmann model predicts glycan structures from lectin binding

2023-06-06

Abstract excerpt

Glycans are complex oligosaccharides involved in many diseases and biological processes. Unfortunately, current methods for determining glycan composition and structure (glycan sequencing) are laborious and require a high level of expertise. Here, we assess the feasibility of sequencing glycans based on their lectin binding fingerprints. By training a Boltzmann model on lectin binding data, we predict the approxim...

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Identifiers and source

Literature Corpus work
29b454b9-159a-5ee0-9e18-7b53e10dc626
DOI
10.1101/2023.06.03.543532
Open publication

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A Boltzmann model predicts glycan structures from lectin bindingDOI 10.1101/2023.06.03.543532
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