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Article

Circulating microRNAs as Putative Causal Regulators of Peripheral Arterial Disease in Diabetic Foot: An Integrative Multi-Omics and Drug Repurposing Study

2026-06-09

Abstract excerpt

<title>Abstract</title> <p>Objective To identify causal circulating miRNAs regulating the immuno-vascular axis in DFU-associated PAD through integrative multi-omics analysis, and to map pharmacologically actionable targets via computational drug repurposing. Methods Publicly available transcriptomic datasets (GEO; n = 312 samples) were analyzed using DESeq2 for differential miRNA expression. Two-sample Mendelia...

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Literature Corpus work
db5a64ec-9662-5e4d-8a20-d4cfa0317dc9
DOI
10.21203/rs.3.rs-9971778/v1
Open publication

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Circulating microRNAs as Putative Causal Regulators of Peripheral Arterial Disease in Diabetic Foot: An Integrative Multi-Omics and Drug Repurposing StudyDOI 10.21203/rs.3.rs-9971778/v1
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