Article
Unraveling shared risk factors for diabetic foot ulcer: a comprehensive Mendelian randomization analysis
1 Nov 2023
Abstract excerpt
INTRODUCTION: Diabetic foot ulcer (DFU) stands as a severe diabetic lower extremity complication, characterized by high amputation rates, mortality, and economic burden. We propose using Mendelian randomization studies to explore shared and distinct risk factors for diabetic lower extremity complications. RESEARCH DESIGN AND METHODS: We selected uncorrelated genetic variants associated with 85 phenotypes in five...
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