Back to search

Article

Integrative Bioinformatics Analysis of MicroRNA Networks in Diabetic Foot Ulcer Healing: Structure-Function Relationships and Therapeutic Target Identification

2025-09-19

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> Diabetic foot ulcers (DFU) affect 15% of diabetic patients globally. While microRNAs (miRNAs) are known regulators of wound healing, comprehensive bioinformatics analysis of their structural determinants and network interactions in DFU pathophysiology remains limited. <h4>Objective</h4> To perform integrative bioinformatics analysis of miRNA networks in DFU healing, chara...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
6a20bb9c-a9b3-5311-a1c0-7825a51ca226
DOI
10.1101/2025.09.18.25336110
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Integrative Bioinformatics Analysis of MicroRNA Networks in Diabetic Foot Ulcer Healing: Structure-Function Relationships and Therapeutic Target IdentificationDOI 10.1101/2025.09.18.25336110
Diabetic Foot: A MicroRNA-Centric ApproachSemantic proximity
Unravelling the Molecular Footprints of Diabetic Foot Ulcers: In Silico Discovery of Key Protein and MicroRNA SignaturesSemantic proximity
Transcriptomics Revealed Differentially Expressed Transcription Factors and MicroRNAs in Human Diabetic Foot UlcersSemantic proximity
Integrative analysis of miRNA and mRNA paired expression profiling of primary fibroblast derived from diabetic foot ulcers reveals multiple impaired cellular functionsSemantic proximity
Understanding molecular mechanisms and miRNA-based targets in diabetes foot ulcersSemantic proximity
Circulating microRNAs as Putative Causal Regulators of Peripheral Arterial Disease in Diabetic Foot: An Integrative Multi-Omics and Drug Repurposing StudySemantic proximity
Integrative Analysis of miRNA Expression Profiling of Diabetic Foot Ulcers Wound Treated With Zizhu OintmentSemantic proximity
Integrative small and long RNA-omics analysis of human healing and non-healing wounds discovers cooperating microRNAs as therapeutic targetsSemantic proximity
MiRNA-122-5p is Upregulated in Diabetic Foot Ulcers and Decelerates the Transition from the Inflammatory to the Proliferative StageSemantic proximity
Bioinformatic Analysis Reveals Hub Immune-Related Genes of Diabetic Foot UlcersSemantic proximity
Exploring microRNAs in diabetic chronic cutaneous ulcers: Regulatory mechanisms and therapeutic potentialSemantic proximity
Comprehensive transcriptomic analysis of immune-related genes in diabetic foot ulcers: New insights into mechanisms and therapeutic targetsSemantic proximity
Select a neighboring publication to make it the new centre.