Article

Neurite outgrowth deficits caused by rare PLXNB1 mutation in pediatric bipolar disorder

2022-05-10

Abstract excerpt

Pediatric Bipolar Disorder (PBD) is a severe mood dysregulation condition that affects 0.5–1% of children and teens in the United States. It is associated with recurrent episodes of psychosis and depression and an increased risk of suicidality. However, the genetics and neuropathology of PBD are largely unknown. Here, we used a combinatorial family-based approach to characterize the cellular, molecular, genetic, a...

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Literature Corpus work: db53c225-b866-5951-9f51-fca3809a3c47
DOI: 10.1101/2022.05.06.22274499

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