Article
Integrative analyses prioritize GNL3 as a risk gene for bipolar disorder.
Molecular psychiatry - 1 Nov 2020
Meng Qingtuan, Wang Le, Dai Rujia, Wang Jiawen, Ren Zongyao, Liu Sihan, Xia Yan, Jiang Yi, Duan Fangyuan, Wang Kangli, Liu Chunyu, Chen Chao
Abstract excerpt
Genome-wide association studies (GWASs) have identified numerous single nucleotide polymorphisms (SNPs) associated with bipolar disorder (BD), but what the causal variants are and how they contribute to BD is largely unknown. In this study, we used FUMA, a GWAS annotation tool, to pinpoint potential causal variants and genes from the latest BD GWAS findings, and performed integrative analyses, including brain...
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