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Article

The low expression of miR-451 predicts a worse prognosis in non-small cell lung cancer cases

12 Jul 2017

Abstract excerpt

PURPOSE: miR-451 is a tumor suppressive microRNA with several target genes, including Macrophage migration inhibitory factor (MIF). As little is known about the expression and clinicopathological significance of mir-451 in NSCLC, we performed a clinicopathological study of 370 NSCLC cases to clarify them. Cell biological experiments were also performed on NSCLC cell lines to confirm the tumor-suppressive role of...

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PMID: 28704499
DOI: 10.1371/journal.pone.0181270

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