Article

Deciphering the genetic and epidemiological landscape of mitochondrial DNA abundance

2020-09-25

Abstract excerpt

Somatically acquired whole chromosome loss in nucleated blood cells is an indicator of immune aging and genomic instability. However, little is known about aging, lifestyle and genetic factors influencing mitochondrial (MT) DNA abundance. In this study, MT DNA abundance was estimated from the weighted intensities of probes mapping to the MT genome in 295,150 participants from the UK Biobank. We found that abundanc...

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Literature Corpus work: daebee7c-ddd2-5949-acfd-6ee38b0a56aa
DOI: 10.1101/2020.09.25.313171

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