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Integrative Clinical and Molecular Characterization of Translocation Renal Cell Carcinoma

2021-04-15

Abstract excerpt

<h4> ABSTRACT </h4> Translocation renal cell carcinoma (tRCC) is an aggressive and poorly-characterized subtype of kidney cancer driven by MiT/TFE gene fusions. Here, we define the landmarks of tRCC through an integrative analysis of 152 tRCC patients identified across multiple genomic, clinical trial, and retrospective cohorts. Most tRCCs harbor few somatic alterations apart from MiT/TFE fusions and homozygou...

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Literature Corpus work
dadc58ea-5e6e-5917-b941-57cd4ada9921
DOI
10.1101/2021.04.14.439908
Open publication

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Integrative Clinical and Molecular Characterization of Translocation Renal Cell CarcinomaDOI 10.1101/2021.04.14.439908
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