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Regulation of interleukin-6 cytokine responses by mitogen activated protein kinases

2014-01-01

Abstract excerpt

Interleukin (IL)-6-type cytokines signal through glycoprotein (gp) 130, which is a key component of their receptor complex. Upon stimulation, gp130 mediates the activation of Janus kinases (JAKs) and signal transducers and activators of transcription (STATs), extracellular signal-regulated kinase (ERK) 1 and ERK2, phosphoinositol-3 kinase (PI3K) and AKTs. Here, it is demonstrated that ERK2, but not ERK1, controls...

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Literature Corpus work
dab8964f-cabc-5286-b9b7-b5989ebafd58
DOI
10.25560/29860
Open publication

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Regulation of interleukin-6 cytokine responses by mitogen activated protein kinasesDOI 10.25560/29860
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