Interleukin 6 and its Receptor: Ten Years Later

Abstract excerpt

Ten years have passed since the molecular cloning of interleukin 6 (IL-6) in 1986. IL-6 is a typical cytokine, exhibiting functional pleiotropy and redundancy. IL-6 is involved in the immune response, inflammation, and hematopoiesis. The IL-6 receptor consists of an IL-6 binding alpha chain and a signal transducer, gp130, which is shared among the receptors for the IL-6 related cytokine subfamily. The sharing of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Pharmacological Effects of Natural Compounds
• Share to interferon and immune responses
• Share to Cytokine Signaling Pathways and Interactions