Article

Exploring Serum Transferrin Regulation of Nonferric Metal Therapeutic Function and Toxicity

2020-08-09

Abstract excerpt

Serum transferrin (sTf) plays a pivotal role in regulating iron biodistribution and homeostasis within the body. The molecular details of sTf Fe(III) binding, blood transport, and cellular delivery through transferrin receptor-mediated endocytosis are generally well-understood. Emerging interest exists in exploring sTf complexation of nonferric metals as it facilitates the therapeutic potential and toxicity of sev...

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Literature Corpus work: da9b8ddc-1f1e-5955-b30c-ec62599e81d3
DOI: 10.20944/preprints202008.0223.v1

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