Article

An investigation into the role of PPARγ and IL-6 in exercise-induced alterations in monocyte gene expression

2015-01-01

Abstract excerpt

The pro-inflammatory M1 macrophage phenotype is linked to insulin resistance, T2D and associated cardiovascular co-morbidities, whereas M2 macrophages regulate the M1 inflammatory response and are, thus, believed to be preventative of these diseases. Exercise may induce markers of M2 polarisation and downregulate M1 markers in mononuclear cells but this has not yet been demonstrated in macrophage precursors, monoc...

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Literature Corpus work: da9a03c4-47ef-5dcd-9924-ff6dce4972cb
DOI: 10.25401/cardiffmet.20286072.v1

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