Article

A lipid-associated macrophage lineage rewires the spatial landscape of adipose tissue in early obesity

2022-02-27

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Obesity-induced metabolic dysfunction, tissue remodelling, and chronic inflammation in visceral white adipose-tissue (WAT) are correlated with insulin resistance, type II diabetes, and metabolic disease pathogenesis [1]. In this work, we sought to establish spatio-temporal context of adipose tissue macrophage (ATM) reprogramming during obesity. <h4>Methods</h4> We captured s...

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Literature Corpus work: 42297544-d3a0-5a3f-b349-ac9c45478618
DOI: 10.1101/2022.02.26.482134

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