Article

TUMOR–PRE-ADIPOCYTE CROSSTALK SUSTAINS BREAST CANCER GROWTH VIA RET SIGNALLING

2026-05-08

Abstract excerpt

<h4>ABSTRACT</h4> Adipose tissue is the dominant stromal component of the breast, yet whether breast tumors exploit adipocyte plasticity to support cancer growth remains unclear. Here, we show that breast tumors actively disturb adipocyte differentiation, generating an immature tumor-adjacent adipose niche enriched in pre-adipocytes that directly promotes tumor progression. In human breast cancer samples, adipocy...

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Literature Corpus work: ae8fecfc-dafd-59b9-8751-f3dbb2788ccc
DOI: 10.64898/2026.05.05.722993

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