Article

Robust Adaptive Deep Brain Stimulation Control of Non-Stationary Cortex-Basal Ganglia-Thalamus Network Models in Parkinson’s Disease

2023-08-21

Abstract excerpt

Closed-loop deep brain stimulation (DBS) is a promising therapy for Parkinson’s disease (PD) that works by adjusting DBS patterns in real time from the guidance of feedback neural activity. Current closed-loop DBS mainly uses threshold-crossing on-off controllers or linear time-invariant (LTI) controllers to regulate the basal ganglia (BG) beta band oscillation power. However, the critical cortex-BG-thalamus netwo...

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Literature Corpus work: da45149d-b869-5624-a601-a3ea5d750a00
DOI: 10.1101/2023.08.20.554043

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