Article

The Virtual Parkinsonian Patient

2024-07-10

Abstract excerpt

<h4> Abstract </h4> This study investigates the influence of the pharmacological nigrostriatal dopaminergic stimula-tion on the entire brain by analyzing EEG and deep electrodes, placed near the subthalamic nuclei, from 10 Parkinsonian patients, before (OFF) and after (ON) L-Dopa administration. We charac-terize large-scale brain dynamics as the spatio-temporal spreading of aperiodic bursts. We then simulate the e...

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Literature Corpus work: c1718956-4ce1-5f19-a3be-401d3d4867e1
DOI: 10.1101/2024.07.08.24309856

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