Article

Subthalamic nucleus encoding steers adaptive therapies for gait in Parkinson’s disease

2025-08-21

Abstract excerpt

<h4>ABSTRACT</h4> Parkinson’s disease leads to a spectrum of cardinal motor symptoms and locomotor deficits that vary in severity with the nature of daily activities and the fluctuating physiology of patients. Many of these deficits remain inadequately addressed by existing therapies that use continuous, activity-agnostic parameters. Instead, adaptive therapies embedding activity-specific parameters have the pote...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 171853c0-31a8-5ba1-abff-341e0b3f2ea1
DOI: 10.1101/2025.08.20.25333478

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Subthalamic nucleus encoding steers adaptive therapies for gait in Parkinson’s diseaseDOI 10.1101/2025.08.20.25333478Read

Device-embedded accelerometry complements neural signals for tracking parkinsonian motor statesSemantic proximity Read

Multitarget brain implants enable generalized decoding of Parkinson’s disease symptoms from chronic home recordingsSemantic proximity Read

Rapid Motor Fluctuations Reveal Short-Timescale Neurophysiological Biomarkers of Parkinson’s DiseaseSemantic proximity Read

Decoding Dynamically Shifting States of Parkinson’s Disease: Tremor, Bradykinesia, and Effective Motor ControlSemantic proximity Read

The effect of Levodopa and Stimulation on post-surgery Freezing of Gait in STN-DBS Parkinson's Disease patients: a clinical and kinematic analysisSemantic proximity Read

At-Home Movement State Classification Using Totally Implantable Bidirectional Cortical-Basal Ganglia Neural InterfaceSemantic proximity Read

Differential Effects of Pathological Beta Burst Dynamics Between Parkinson’s Disease Phenotypes Across Different MovementsSemantic proximity Read

Subthalamic beta bursts correlate with dopamine-dependent motor symptoms in 106 Parkinson's patientsSemantic proximity Read

Deep neurobehavioral phenotyping uncovers neural fingerprints of locomotor deficits in Parkinson’s diseaseSemantic proximity Read

Levodopa-related physiomarkers during deep brain stimulation in Parkinson’s diseaseSemantic proximity Read

Average beta burst duration profiles provide a signature of dynamical changes between the ON and OFF medication states in Parkinson’s diseaseSemantic proximity Read

Impaired Predictive Neuromuscular Control During Sit-to-Walk in Parkinson’s Disease: An Explainable Artificial Intelligence Approach Using Wavelet-Transformed Surface ElectromyographySemantic proximity Read