Article

Pivotal involvement of the CX3CL1-CX3CR1 axis for the recruitment of M2-TAMs in skin carcinogenesis

2019-07-14

Abstract excerpt

<h4>ABSTRACT</h4> We previously revealed the crucial roles of CX3CL1-CX3CR1 axis in skin wound healing. Although repeated wounds frequently develop into skin cancer, the roles of CX3CL1 in skin carcinogenesis remain elusive. Here, we proved that CX3CL1 protein expression and CX3CR1 + macrophages were observed in human skin cancer tissues. Similarly, we observed the enhancement of CX3CL1 expression and the abunda...

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Literature Corpus work: da07bd07-bb59-5676-b7c2-0899d57e614d
DOI: 10.1101/700914

Open publication

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