Article

Studies on the regulation of tissue plasminogen activator activity by physiological templates

2012-01-01

Abstract excerpt

Myocardial infarction (MI) and ischemic stroke (IS) are caused by blood clots blocking arteries and cutting off the blood supply to tissues in the heart or brain. Clots may be cleared using plasminogen activators (“clot busters”) that convert plasminogen into plasmin, which in turn digests fibrin. The major plasminogen activator in the circulation is tissue plasminogen activator (tPA) and a recombinant form Altepl...

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Literature Corpus work: d9fe08a3-5d53-5d9d-a9a4-ab853d75564e
DOI: 10.25560/9595

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