Article

Dexamethasone promotes breast cancer stem cells in obese and not lean mice

2021-06-18

Abstract excerpt

Obesity is highly prevalent in breast cancer patients and it is associated with increased recurrence and breast cancer specific mortality. Glucocorticoid (GC) use, in addition to obesity is associated with promoting breast cancer metastasis through activation of stemness-related pathways. Therefore, we utilised the synergetic allograft E0771 breast cancer model to investigate if treatment with GCs had differential...

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Literature Corpus work: d9b9176c-ec7d-5651-82b3-3918412143e9
DOI: 10.1101/2021.06.18.449008

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