Article

C/EBPδ demonstrates a dichotomous role in tumor initiation and promotion of epithelial carcinoma

2019-01-23

Abstract excerpt

C/EBPδ (CEBPD), a gene part of the highly conserved basic-leucine zipper (b-ZIP) domain of transcriptional factors, is downregulated in 65% of high grade serous carcinoma of the ovary (HGSC). Overexpression of C/EBPδ in different tumors as glioblastoma and breast cancer either promotes tumor progression or inhibits growth. Despite these contradictory roles in different cancer types, we show that C/EBPδ overexpre...

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Literature Corpus work: d982a1fd-719d-5fe9-b406-e018026ab0cf
DOI: 10.1101/528885

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