Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CEBP Epigenetic Dysregulation as a Drug Target for the Treatment of Hematologic and Gynecologic Malignancies.

Current drug targets - 1 Jan 2017

Sun Chengming, Duan Ping, Luan Caifu

Abstract excerpt

BACKGROUND: The CCAAT/enhancer binding proteins (C/EBPs) form a family of transcription factors regulating many genes' expression in a variety of cells/tissues/organs at different developmental stages. With their capability of binding to their cognate DNA elements and through protein-protein interactions, C/EBPs modulate diverse functions including cell differentiation, metabolism, and immune response, under both...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to CCAAT-Enhancer-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Epigenesis, Genetic

Share to Gene Expression Regulation, Neoplastic

Share to Genital Neoplasms, Female

Share to Hematologic Neoplasms

Share to Molecular Targeted Therapy

Source

Identifiers

PMID: 28031014
DOI: 10.2174/1389450117666161228160455

Genes

EBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CEBP Epigenetic Dysregulation as a Drug Target for the Treatment of Hematologic and Gynecologic Malignancies.PMID 28031014Read ↗

[Roles of CEBPA mutation and expression abnormality in acute myeloid leukemia - review].Semantic proximity Read ↗

The Many Faces of C/EBPδ and their Relevance for Inflammation and CancerSemantic proximity Read ↗

Expression and regulation of C/EBPα in normal myelopoiesis and in malignant transformation.Semantic proximity Read ↗

The E2F family: specific functions and overlapping interests.Semantic proximity Read ↗

The role of E2F2 in cancer progression and its value as a therapeutic targetSemantic proximity Read ↗

Profiling of Discrete Gynecological Cancers Reveals Novel Transcriptional Modules and Common Features Shared by Other Cancer Types and Embryonic Stem CellsSemantic proximity Read ↗

Role of E2F transcription factor in oral cancer: Recent insight and advancementsSemantic proximity Read ↗

C/EBPδ demonstrates a dichotomous role in tumor initiation and promotion of epithelial carcinomaSemantic proximity Read ↗

The E2F transcription factor 2: What do we know?Semantic proximity Read ↗

Epigenomics, Pharmacoepigenomics, and Personalized Medicine in Cervical Cancer.Semantic proximity Read ↗

C/EBPα deregulation as a paradigm for leukemogenesis.Semantic proximity Read ↗

The C/EBP family of transcription factors: a paradigm for interaction between gene expression and proliferation control.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.