Article

C1orf61 promotes hepatocellular carcinoma metastasis and affects the therapeutic response to sorafenib

2020-09-24

Abstract excerpt

<h4>Background: </h4> C1orf61 is a specific transcriptional activator that is highly up-regulated during weeks 4–9 of human embryogenesis, the period in which most organs develop. We have previously demonstrated that C1orf61 acts as a tumor activator in human hepatocellular carcinoma (HCC) tumorigenesis and metastasis. However, the underlying molecular mechanisms of tumor initiation and progression in HCC remain o...

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Literature Corpus work: 6504adae-6af3-5cf5-8b71-271358cd22c9
DOI: 10.21203/rs.3.rs-80702/v1

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