Article

Tumor RNA-Transfected Dendritic Cells Generated From Induced Pluripotent Stem Cells Induces Anti-Tumor Immunity

2021-10-05

Abstract excerpt

Significant efficacy of induced pluripotent stem cells (iPSCs) in generating DCs for cancer vaccine therapy was suggested in our previous studies. In clinical application of DC vaccine therapy, however, few DC vaccine systems have shown strong clinical response. To enhance immunogenicity in the DC vaccine, we transfected patient-derived iPSDCs with in vitro transcriptional RNA (ivtRNA), which was obtained from tum...

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Literature Corpus work: d90e4469-8f68-5380-8f53-44277b518413
DOI: 10.21203/rs.3.rs-923680/v1

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