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Impact of <i>AKR1C2</i> and <i>AKR1C3</i> single nucleotide polymorphism rs28571848 in adipose tissues of individuals with severe obesity

2025-10-14

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Adipose tissue androgen turnover, dictated at least in part by the enzymes AKR1C2 and AKR1C3, has been linked to abdominal obesity. Recently, we investigated a single-nucleotide polymorphism (SNP) named rs28571858, that might increase AKR1C2 and AKR1C3 expression in human adipose tissue. Here, we studied the impact of rs28571848 on adipose tissue function and cardiometabolic...

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Literature Corpus work
d90d310a-4378-5699-99d3-807c5168a1ba
DOI
10.1101/2025.10.10.25337731
Open publication

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Impact of <i>AKR1C2</i> and <i>AKR1C3</i> single nucleotide polymorphism rs28571848 in adipose tissues of individuals with severe obesityDOI 10.1101/2025.10.10.25337731
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