Article

Metabolomic signature of angiopoietin-like protein 3 deficiency in fasting and postprandial state

2018-10-13

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Loss-of-function variants in the angiopoietin-like 3 gene ( ANGPTL3 ) have been associated with low levels of plasma lipoproteins and decreased coronary artery disease risk. We aimed to determine detailed metabolic effects of genetically-induced ANGPTL3 deficiency in fasting and postprandial state. <h4>Approach and Results</h4> We studied individuals carrying S17X loss-of-...

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Literature Corpus work: d900c5d2-f5c4-5a07-9f1c-00ce1e17708f
DOI: 10.1101/441857

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