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Article

Effects of angiopoietin-like protein 3 deficiency on postprandial lipid and lipoprotein metabolism.

Journal of lipid research - 1 Jun 2016

Minicocci Ilenia, Tikka Anna, Poggiogalle Eleonora, Metso Jari, Montali Anna, Ceci Fabrizio, Labbadia Giancarlo, Fontana Mario, Di Costanzo Alessia, Maranghi Marianna, Rosano Aldo, Ehnholm Christian, Donini Lorenzo Maria, Jauhiainen Matti, Arca Marcello

Abstract excerpt

The consequences of angiopoietin-like protein 3 (ANGPTL3) deficiency on postprandial lipid and lipoprotein metabolism has not been investigated in humans. We studied 7 homozygous (undetectable circulating ANGPTL3 levels) and 31 heterozygous (50% of circulating ANGPTL3 levels) subjects with familial combined hypolipidemia (FHBL2) due to inactivating ANGPTL3 mutations in comparison with 35 controls. All subjects...

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Identifiers

PMID: 27040449
DOI: 10.1194/jlr.P066183
PMCID: PMC4878193

Genes

ANGPTL3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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