Article

Extracellular Matrix-Guided Tumor Stratification and Network Models Reveal Clinical Molecular Grades

2025-09-03

Abstract excerpt

<h4>ABSTRACT</h4> The extracellular matrix (ECM) critically shapes tumor fate and treatment outcome, serving as a potent prognostic factor. Yet, its compositional heterogeneity across tumors makes it difficult to assess its impact on tumor dynamics. To address this, we introduce an ECM-guided patient stratification pipeline through integration of multi-omic data in lung cancer patients. We obtained four patient g...

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Literature Corpus work: d8d9aaaa-429b-5400-acf1-b260d4e4410a
DOI: 10.1101/2025.08.29.672994

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