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Deciphering the role of the chitin synthase families 1 and 2 in thein vivoandin vitrogrowth ofAspergillus fumigatusby multiple gene targeting deletion

20 Jun 2014

Abstract excerpt

Although chitin is an essential component of the fungal cell wall (CW), its biosynthesis and role in virulence is poorly understood. In Aspergillus fumigatus, there are eight chitin synthase (CHS) genes belonging to two families CHSA-C, CHSG in family 1 and CHSF, CHSD, CSMA, CSMB in family 2). To understand the function of these CHS genes, their single and multiple deletions were performed using β-rec/six system...

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PMID: 24946720
DOI: 10.1111/cmi.12326

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Deciphering the role of the chitin synthase families 1 and 2 in thein vivoandin vitrogrowth ofAspergillus fumigatusby multiple gene targeting deletionPMID 24946720Read ↗

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