Back to search

Article

The HosA histone deacetylase regulates stress resistance, host cell interactions, and virulence in <i>Aspergillus fumigatus</i>

2025-11-19

Abstract excerpt

The capacity of Aspergillus fumigatus to cause invasive pulmonary aspergillosis depends on its ability to adapt to dynamic and stressful microenvironments within the host. Epigenetic regulation, including histone deacetylation, plays a critical role in fungal adaptation to stress. Here, we investigated the role of the class I histone deacetylase (HDAC) HosA in A. fumigatus stress resistance, host cell interactio...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
6e32144e-2cc5-5657-a24c-ab4639a69cea
DOI
10.1101/2025.11.19.689210
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The HosA histone deacetylase regulates stress resistance, host cell interactions, and virulence in <i>Aspergillus fumigatus</i>DOI 10.1101/2025.11.19.689210
A Class 1 Histone Deacetylase as Major Regulator of Secondary Metabolite Production in Aspergillus nidulansSemantic proximity
The MYST Family Histone Acetyltransferase SasC Governs Diverse Biological Processes in Aspergillus fumigatusSemantic proximity
The Candida albicans Histone Acetyltransferase Hat1 Regulates Stress Resistance and Virulence via Distinct Chromatin Assembly PathwaysSemantic proximity
Histone acetyltransferases and deacetylases are required for virulence, conidiation, DNA damage repair, and multiple stresses resistance of <i>Alternaria alternata</i>Semantic proximity
Histone acetyltransferase Sas3 contributes to fungal development, cell wall integrity, and virulence in Aspergillus fumigatusSemantic proximity
The MYST Family Histone Acetyltransferase Sas3 Governs Diverse Biological Processes in <em>Aspergillus fumigatus</em>Semantic proximity
Sirtuin E deacetylase is required for full virulence of Aspergillus fumigatusSemantic proximity
The sulfur-related metabolic status of <i>Aspergillus fumigatus</i> during infection reveals cytosolic serine hydroxymethyltransferase as a promising antifungal targetSemantic proximity
Histone Acetyltransferases and Deacetylases Are Required for Virulence, Conidiation, DNA Damage Repair, and Multiple Stresses Resistance of Alternaria alternataSemantic proximity
A Ssd1 homolog impacts trehalose and chitin biosynthesis and contributes to virulence in <i>Aspergillus fumigatus</i>Semantic proximity
Effects of Hst3p inhibition in Candida albicans: a genome-wide H3K56 acetylation analysisSemantic proximity
Histone Acetylation/Deacetylation in Candida Albicans and their Potential as Antifungal TargetsSemantic proximity
Select a neighboring publication to make it the new centre.