Article

Longitudinal tracking of acute kidney injury reveals injury propagation along the nephron

2023-01-24

Abstract excerpt

<title>Abstract</title> <p>Acute kidney injury (AKI) is an important risk factor for chronic kidney disease (CKD), but the underlying mechanisms of failed tubule repair and AKI-CKD-transition are incompletely understood. In this study, we aimed for dynamic tracking of tubule injury and remodeling to understand if focal injury upon AKI may spread over time. Here we present a novel model of AKI, in which we rendere...

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Literature Corpus work: d899ec09-ecf2-5082-8b3a-077e0a0804de
DOI: 10.21203/rs.3.rs-2487613/v1

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